Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.35 |
| ▸ | PARP1 | P09874 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30726152 | 0.79 | P4HB (0.40) | HTR2APARP1P4HBMEN1KMT2A | |
| SCHEMBL30726149 | 0.72 | P4HB (0.47) | HTR2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL24455315 | 0.69 | CES2 (0.45) | PARP14PARP1CES2CES1 | |
| SCHEMBL6186161 | 0.67 | PARP1 (0.41) | PARP14PARP1CES2CES1 | |
| SCHEMBL10160070 | 0.67 | POLB (0.45) | PARP1POLBL3MBTL1CES2CES1 | |
| SCHEMBL477698 | 0.66 | CES2 (0.68) | PARP1CES2CES1 | |
| SCHEMBL15094272 | 0.65 | KCNJ6 (0.36) | PARP1CES2CES1 | |
| SCHEMBL29088228 | 0.63 | PARP1 (0.43) | PARP1CES2CES1MEN1KMT2A | |
| SCHEMBL29851114 | 0.63 | PARP1 (0.43) | PARP1CES2CES1MEN1KMT2A | |
| SCHEMBL22169000 | 0.63 | PARP1 (0.40) | PARP14PARP1L3MBTL1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425644-A | Opioid receptor modulators | 埃皮欧黛公司 | 2024-01-19 | — | — | CN | disclosed |