SCHEMBL30726751

SCHEMBL30726751

c1ccc2c(c1)ccc1cc3[nH]cnc3cc12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
HSD17B10 Q99714 3/20 0.50
HIF1A Q16665 1/20 0.50
CYP1B1 Q16678 1/20 0.50
QPCT Q16769 3/20 0.45
KDM4E B2RXH2 4/20 0.43
MAPT P10636 4/20 0.43
TDP1 Q9NUW8 2/20 0.43
RECQL P46063 2/20 0.43
QPCTL Q9NXS2 2/20 0.43
APEX1 P27695 1/20 0.43
BLM P54132 1/20 0.43
SMN1; SMN2 Q16637 5/20 0.42
HPGD P15428 4/20 0.42
RAB9A P51151 3/20 0.42
NPC1 O15118 2/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2A6 P11509 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4144088 0.93 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1QPCT
SCHEMBL4132133 0.81 KDM4E (0.52) ALDH1A1HSD17B10QPCTKDM4EMAPT
Phenanthrene SCHEMBL28066912 0.80 SMN1; SMN2 (0.48) ALDH1A1HSD17B10HIF1ACYP1B1QPCT
Bromide SCHEMBL23726605 0.80 KDM4E (0.50) ALDH1A1HSD17B10QPCTKDM4EMAPT
SCHEMBL11785873 0.78 MAPT (0.49) ALDH1A1QPCTKDM4EMAPTTDP1
SCHEMBL27824936 0.77 QPCT (0.59) ALDH1A1QPCTKDM4EQPCTLSMN1; SMN2
SCHEMBL27824939 0.77 QPCT (0.46) ALDH1A1QPCTKDM4EQPCTLSMN1; SMN2
SCHEMBL7865073 0.77 LMNA (0.48) ALDH1A1QPCTKDM4EMAPTQPCTL
Chrysene SCHEMBL28161443 0.77 HPRT1 (0.50) ALDH1A1HSD17B10QPCTKDM4EMAPT
SCHEMBL27824985 0.76 ALOX5 (0.46) ALDH1A1QPCTKDM4EMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024044327-A1 DHNT MONOMERS AND POLYMER DYES WITH MODIFIED PHOTOPHYSICAL PROPERTIES BECKMAN COULTER, INC. (US) 2024-02-29 WO disclosed