Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 12/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 9/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 9/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPC | P11150 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30727739 | 0.90 | PIK3CA (0.41) | PDE10APDE3BPDE3AKRASPIK3CA | |
| SCHEMBL30727682 | 0.81 | PIK3CD (0.39) | PDE10APDE3BPDE3AKRASPIK3CA | |
| SCHEMBL30727695 | 0.80 | PIK3CD (0.38) | PDE10APDE3BPDE3AEGFRKRAS | |
| SCHEMBL30727616 | 0.78 | LPL (0.40) | PDE10APDE3BPDE3AEGFRKRAS | |
| SCHEMBL30727651 | 0.77 | PDE10A (0.46) | PDE10APDE3BPDE3AKRASPIK3CA | |
| Formic Acid SCHEMBL30727697 | 0.75 | LPL (0.39) | PDE10APDE3BPDE3AEGFRKRAS | |
| SCHEMBL30727769 | 0.72 | PIK3CA (0.39) | KRASPIK3CAKDM4EALDH1A1MAPT | |
| SCHEMBL30727745 | 0.72 | KRAS (0.37) | KRASPIK3CAKDM4EALDH1A1MAPK1 | |
| SCHEMBL30727669 | 0.69 | KRAS (0.39) | KRASPIK3CAKDM4EALDH1A1MAPT | |
| SCHEMBL31399866 | 0.67 | ALDH1A1 (0.42) | KRASKDM4EALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532495-A1 | CD73 INHIBITOR COMPOUNDS | Adorx therapeutics Limited (GB) | 2025-04-09 | — | — | EP | disclosed |
| CN-119585273-A | CD73 inhibitor compounds | 阿道尔克斯治疗有限公司 | 2025-03-07 | — | — | CN | disclosed |
| WO-2023233130-A1 | CD73 INHIBITOR COMPOUNDS | AdoRx Therapeutics Limited (GB) | 2023-12-07 | — | — | WO | disclosed |