Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPC | P11150 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30727616 | 0.96 | LPL (0.40) | LPLLIPCLIPGALDH1A1KDM4E | |
| SCHEMBL31399866 | 0.86 | ALDH1A1 (0.42) | ALDH1A1KDM4ESMN1; SMN2MAPTMAPK1 | |
| SCHEMBL30727648 | 0.82 | KDM4E (0.37) | LIPGALDH1A1KDM4ESMN1; SMN2MAPT | |
| Formic Acid SCHEMBL30727763 | 0.80 | KIT (0.36) | ALDH1A1MAPK1KRASPOLBHTT | |
| SCHEMBL30727599 | 0.78 | KDM4E (0.37) | ALDH1A1KDM4ESMN1; SMN2MAPK1MEN1 | |
| SCHEMBL30727708 | 0.77 | LRRK2 (0.40) | ALDH1A1KDM4ESMN1; SMN2MAPTMAPK1 | |
| SCHEMBL30727577 | 0.76 | KIT (0.38) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL30727802 | 0.76 | ENPP1 (0.40) | ALDH1A1KDM4ESMN1; SMN2MAPTMAPK1 | |
| SCHEMBL30727686 | 0.75 | PDE10A (0.42) | LPLLIPCLIPGALDH1A1KDM4E | |
| SCHEMBL30727620 | 0.74 | PDE10A (0.41) | PDE3BPDE3APDE10AKRASLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250340565-A1 | CD73 INHIBITOR COMPOUNDS | ADORX THERAPEUTICS LTD (GB) | 2025-11-06 | — | — | US | disclosed |
| EP-4532495-A1 | CD73 INHIBITOR COMPOUNDS | Adorx therapeutics Limited (GB) | 2025-04-09 | — | — | EP | disclosed |
| CN-119585273-A | CD73 inhibitor compounds | 阿道尔克斯治疗有限公司 | 2025-03-07 | — | — | CN | disclosed |
| WO-2023233130-A1 | CD73 INHIBITOR COMPOUNDS | AdoRx Therapeutics Limited (GB) | 2023-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250340565-A1 | CD73 INHIBITOR COMPOUNDS | ENTPD5, ENTPD1, NT5E | LPL 2411/4885LIPC 2674/4885LIPG 1763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.