SCHEMBL30728581

SCHEMBL30728581

Cc1ccc(C(=CSC=C(c2ccc(C)cc2)c2ccc(C)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.50
CES1 P23141 3/20 0.50
ALDH1A1 P00352 6/20 0.44
HTT P42858 3/20 0.44
NPSR1 Q6W5P4 3/20 0.44
LMNA P02545 3/20 0.44
TDP1 Q9NUW8 3/20 0.44
PKM P14618 2/20 0.44
ATM Q13315 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HPGD P15428 2/20 0.44
NLRP1 Q9C000 1/20 0.44
MEN1 O00255 1/20 0.44
NTSR1 P30989 1/20 0.44
KMT2A Q03164 1/20 0.44
ACHE P22303 2/20 0.40
PTGS2 P35354 1/20 0.40
GAA P10253 1/20 0.39
MAPT P10636 2/20 0.39
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30728586 0.83 CES2 (0.58) CES2CES1ALDH1A1NPSR1LMNA
SCHEMBL29532048 0.76 CES2 (0.50) CES2CES1ALDH1A1HTTNPSR1
SCHEMBL6763915 0.76 ALDH1A1 (0.50) CES2CES1ALDH1A1HTTNPSR1
SCHEMBL30728585 0.75 CES2 (0.50) CES2CES1ALDH1A1LMNAMAPT
SCHEMBL516740 0.72 ALDH1A1 (0.46) CES2CES1ALDH1A1HTTNPSR1
SCHEMBL8053369 0.70 PTGS2 (0.69) CES2CES1ALDH1A1HTTNPSR1
SCHEMBL2925327 0.70 PTGS2 (0.69) CES2CES1ALDH1A1HTTNPSR1
SCHEMBL8154212 0.68 ALDH1A1 (0.43) CES2CES1ALDH1A1HTTNPSR1
SCHEMBL16922640 0.68 ALDH1A1 (0.43) CES2CES1ALDH1A1HTTNPSR1
SCHEMBL9421083 0.68 ALDH1A1 (0.48) CES2CES1ALDH1A1HTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117447370-A Preparation method of aggregation-induced emission material tetraaryl divinyl sulfide 山西蓬勃健康科技有限公司 2024-01-26 CN disclosed