Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPR1 | P16066 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 8/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30728630 | 1.00 | BLM (0.37) | BLMTP53CYP1A2CYP3A4PKM | |
| SCHEMBL22482352 | 0.79 | KDM1A (0.32) | HTT | |
| SCHEMBL15957201 | 0.79 | NISCH (0.42) | — | |
| SCHEMBL28410901 | 0.79 | NISCH (0.42) | — | |
| SCHEMBL15956923 | 0.75 | RIPK1 (0.44) | BLMTP53CYP1A2CYP3A4PKM | |
| SCHEMBL21156931 | 0.75 | TP53 (0.35) | BLMTP53CYP1A2CYP3A4PKM | |
| SCHEMBL15956922 | 0.75 | RIPK1 (0.44) | BLMTP53CYP1A2CYP3A4PKM | |
| SCHEMBL31089995 | 0.74 | BLM (0.43) | BLMTP53CYP1A2CYP3A4PKM | |
| SCHEMBL30076378 | 0.74 | ADRA1A (0.35) | CYP3A4LMNAMAPT | |
| Hydrochloric Acid SCHEMBL20477358 | 0.74 | RIPK1 (0.43) | BLMTP53CYP1A2CYP3A4PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120192310-A | Benzene as RIPK1 inhibitor and oxazepine compounds | 南京天印健华医药科技有限公司 | 2025-06-24 | — | — | CN | disclosed |
| CN-117447460-A | Heterocyclic compounds as RIPK1 inhibitors | 南京天印健华医药科技有限公司 | 2024-01-26 | — | — | CN | disclosed |