Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.58 |
| ▸ | MAOB | P27338 | 4/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23409228 | 1.00 | MAOA (0.58) | MAOAMAOBACHECHRM2CHRM4 | |
| SCHEMBL23409234 | 0.83 | LMNA (0.49) | CHRM1DRD2DRD3 | |
| SCHEMBL23409205 | 0.82 | DRD3 (0.62) | MAOAMAOBDRD2DRD4DRD3 | |
| SCHEMBL23409975 | 0.81 | DRD2 (0.53) | DRD2DRD4DRD3 | |
| SCHEMBL23409561 | 0.81 | HRH3 (0.46) | MAOAMAOB | |
| SCHEMBL23409211 | 0.81 | DRD2 (0.53) | MAOBDRD2DRD4DRD3 | |
| SCHEMBL23409236 | 0.80 | DRD2 (0.62) | MAOAMAOBACHECHRM2CHRM1 | |
| SCHEMBL30728639 | 0.80 | DRD2 (0.62) | MAOAMAOBACHECHRM2CHRM1 | |
| SCHEMBL30728641 | 0.77 | DRD2 (0.67) | DRD2 | |
| SCHEMBL23409242 | 0.77 | DRD2 (0.61) | MAOAMAOBACHECHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728956-B | Fused heterocyclic derivative and application thereof | 上海枢境生物科技有限公司 | 2024-01-12 | — | — | CN | disclosed |