Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21330295 | 1.00 | DGAT2 (0.31) | DGAT2NR4A2RORCHTR1AHTR2A | |
| SCHEMBL21330262 | 0.86 | ALOX5 (0.31) | HTR1AHTR2AHTR7 | |
| SCHEMBL29563064 | 0.86 | ALOX5 (0.31) | HTR1AHTR2AHTR7 | |
| SCHEMBL29563888 | 0.84 | HTR1A (0.34) | HTR1AHTR2AHTR7 | |
| SCHEMBL31691821 | 0.82 | HTR1A (0.38) | HTR1AHTR2AHTR7 | |
| SCHEMBL1600282 | 0.82 | HTR1A (0.34) | HTR1AHTR2AHTR7 | |
| SCHEMBL1813909 | 0.79 | HTR1A (0.42) | HTR1AHTR2AHTR7 | |
| SCHEMBL30206827 | 0.79 | HTR1A (0.42) | HTR1AHTR2AHTR7 | |
| SCHEMBL23247178 | 0.78 | WEE1 (0.31) | HTR7 | |
| SCHEMBL20892194 | 0.78 | CCR1 (0.39) | RORCHTR1AHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025226545-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | PRETZEL THERAPEUTICS, INC. (US) | 2025-10-30 | — | — | WO | disclosed |
| EP-4543544-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | Biogen MA Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| CN-119866338-A | Tyrosine kinase 2 inhibitors and uses thereof | 渤健马萨诸塞州股份有限公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-112142747-B | Pyrazolopyrimidine compound, and preparation method and application thereof | 上海医药集团股份有限公司 | 2024-03-01 | — | — | CN | disclosed |
| WO-2023250064-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-12-28 | — | — | WO | disclosed |