Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | CASP3 | P42574 | 2/20 | 0.65 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.65 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.65 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4109053 | 1.00 | NPC1 (0.68) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL10226025 | 0.96 | NPC1 (0.68) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL26053039 | 0.94 | NPC1 (0.66) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL10226020 | 0.88 | NPC1 (0.68) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL10226021 | 0.88 | NPC1 (0.68) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL5053299 | 0.87 | NPC1 (0.87) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL28416625 | 0.85 | NPC1 (0.83) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL8304969 | 0.83 | NPC1 (0.80) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL10831719 | 0.83 | KDM4E (0.61) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL10831846 | 0.83 | CYP1A1 (0.61) | NPC1RAB9AKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377478-A | Methods and compositions for regenerating hair cells in the inner ear of an adult mammal | 麻省眼耳科医院 | 2024-01-09 | — | — | CN | disclosed |