Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.80 |
| ▸ | RAB9A | P51151 | 6/20 | 0.80 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | CASP3 | P42574 | 2/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.62 |
| ▸ | VCP | P55072 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28461746 | 0.94 | NPC1 (0.78) | NPC1RAB9AMEN1KMT2APOLB | |
| 2-Phenyl-1H-Indole SCHEMBL341378 | 0.89 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2APOLB | |
| 2-Phenyl-1H-Indole SCHEMBL29363616 | 0.89 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL30315804 | 0.87 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL3628278 | 0.87 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2APOLB | |
| 2-Phenyl-1H-Indole SCHEMBL28844905 | 0.87 | NPC1 (0.96) | NPC1RAB9AMEN1KMT2APOLB | |
| 2-Phenyl-1H-Indole SCHEMBL6529483 | 0.87 | NPC1 (0.96) | NPC1RAB9AMEN1KMT2APOLB | |
| 2-Phenyl-1H-Indole SCHEMBL29642295 | 0.87 | NPC1 (0.96) | NPC1RAB9AMEN1KMT2APOLB | |
| 2-Phenyl-1H-Indole SCHEMBL11652520 | 0.87 | NPC1 (0.96) | NPC1RAB9AMEN1KMT2APOLB | |
| 2-Phenyl-1H-Indole SCHEMBL29788796 | 0.87 | NPC1 (0.96) | NPC1RAB9AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9637425-B2 | NCN trianionic pincer complexes as catalysts for olefin polymerization and isomerization | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-05-02 | — | — | US | disclosed |
| US-9637425-B2 | NCN trianionic pincer complexes as catalysts for olefin polymerization and isomerization | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-05-02 | — | — | US | disclosed |
| US-20130289326-A1 | NCN TRIANIONIC PINCER COMPLEXES AS CATALYSTS FOR OLEFIN POLYMERIZATION AND ISOMERIZATION | NATIONAL SCIENCE FOUNDATION | 2013-10-31 | — | — | US | disclosed |
| US-20130289326-A1 | NCN TRIANIONIC PINCER COMPLEXES AS CATALYSTS FOR OLEFIN POLYMERIZATION AND ISOMERIZATION | NATIONAL SCIENCE FOUNDATION | 2013-10-31 | — | — | US | disclosed |
| EP-0650599-B1 | METHOD OF COLORIMETRIC ANALYSIS OF MALONIC DIALDEHYDE AND 4-HYDROXY-2-ENALDEHYDES AS INDEXES OF LIPID PEROXIDATION, KITS FOR CARRYING OUT SAID METHOD, SUBSTITUTED INDOLES FOR USE IN SAID METHOD AND THEIR PREPARATION | OXIS ISLE OF MAN LIMITED (GB) | 1999-11-03 | — | — | EP | disclosed |
| US-5726063-A | Method of colorimetric analysis of malonic dialdehyde and 4-hydroxy-2-enaldehydes as indexes of lipid peroxidation, kits for carrying out said method, substituted indoles for use in said method and their preparation | OXIS ISLE OF MAN, LIMITED (US) | 1998-03-10 | — | — | US | disclosed |
| EP-0650599-A1 | METHOD OF COLORIMETRIC ANALYSIS OF MALONIC DIALDEHYDE AND 4-HYDROXY-2-ENALDEHYDES AS INDEXES OF LIPID PEROXIDATION, KITS FOR CARRYING OUT SAID METHOD, SUBSTITUTED INDOLES FOR USE IN SAID METHOD AND THEIR PREPARATION | OXIS INTERNATIONAL S.A. (FR) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994027155-A1 | METHOD OF COLORIMETRIC ANALYSIS OF MALONIC DIALDEHYDE AND 4-HYDROXY-2-ENALDEHYDES AS INDEXES OF LIPID PEROXIDATION, KITS FOR CARRYING OUT SAID METHOD, SUBSTITUTED INDOLES FOR USE IN SAID METHOD AND THEIR PREPARATION | BIOXYTECH (FR) | 1994-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130289326-A1 | NCN TRIANIONIC PINCER COMPLEXES AS CATALYSTS FOR OLEFIN POLYMERIZATION AND ISOMERIZATION | PNN, NCAPH, NCLN | NPC1 275/4885RAB9A 4036/4885MEN1 3908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.