Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PRKDC | P78527 | 10/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515927 | 0.72 | AKR1C3 (0.65) | NPC1RAB9APKMMAPTKDM4E | |
| SCHEMBL3408091 | 0.71 | RAB9A (0.74) | NPC1RAB9APKMMAPTKDM4E | |
| SCHEMBL5963207 | 0.71 | ALDH1A1 (0.58) | NPC1RAB9APKMMAPTKDM4E | |
| SCHEMBL30729279 | 0.70 | NPC1 (0.59) | NPC1RAB9APKMMAPTKDM4E | |
| SCHEMBL28286793 | 0.67 | AKR1C3 (0.54) | NPC1RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL14212567 | 0.67 | ALDH1A1 (0.47) | NPC1RAB9APKMMAPTKDM4E | |
| SCHEMBL11531976 | 0.67 | AKR1C3 (0.59) | NPC1RAB9APKMMAPTKDM4E | |
| SCHEMBL721718 | 0.67 | SMN1; SMN2 (0.44) | NPC1RAB9APKMMAPTKDM4E | |
| SCHEMBL29173466 | 0.66 | AKR1C3 (0.57) | NPC1RAB9APKMMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL9937226 | 0.66 | SMN1; SMN2 (0.43) | NPC1RAB9APKMMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377478-A | Methods and compositions for regenerating hair cells in the inner ear of an adult mammal | 麻省眼耳科医院 | 2024-01-09 | — | — | CN | disclosed |