Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515927 | 0.89 | AKR1C3 (0.65) | AKR1C3MEN1KMT2AHSD17B10MGLL | |
| SCHEMBL11531976 | 0.83 | AKR1C3 (0.59) | AKR1C3MEN1KMT2AHSD17B10MGLL | |
| SCHEMBL29173466 | 0.82 | AKR1C3 (0.57) | AKR1C3MEN1KMT2AHSD17B10MGLL | |
| SCHEMBL13370287 | 0.79 | MAPT (0.50) | MEN1KMT2AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL17279013 | 0.79 | CYP1A1 (0.64) | AKR1C3MEN1KMT2AHSD17B10MGLL | |
| SCHEMBL2218088 | 0.78 | LMNA (0.75) | AKR1C3MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL11504798 | 0.78 | ALDH1A1 (0.46) | MEN1KMT2AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL28242056 | 0.77 | LMNA (0.46) | AKR1C3MEN1KMT2AMGLLALDH1A1 | |
| SCHEMBL29259189 | 0.77 | LMNA (0.79) | AKR1C3MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL9093746 | 0.77 | LMNA (0.71) | MEN1KMT2AHSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476669-A | Lim kinase inhibitor | 富荣吉有限责任公司 | 2019-03-15 | — | — | CN | disclosed |