SCHEMBL30729474

SCHEMBL30729474

N#Cc1ccc(Cl)c([N+](=O)[O-])c1Cl

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 5/20 0.54
TSHR P16473 2/20 0.44
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 2/20 0.39
HSD17B10 Q99714 1/20 0.37
MAPT P10636 1/20 0.36
TRPV4 Q9HBA0 1/20 0.36
PIN1 Q13526 1/20 0.36
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2A Q12879 1/20 0.35
GRIN2B Q13224 1/20 0.35
GRIN2C Q14957 1/20 0.35
GRIN3A Q8TCU5 1/20 0.35
DCTPP1 Q9H773 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
HTR2B P41595 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30729475 1.00 VCAM1 (0.54) VCAM1TSHRTDP1ALDH1A1HSD17B10
SCHEMBL21808022 1.00 VCAM1 (0.54) VCAM1TSHRTDP1ALDH1A1HSD17B10
SCHEMBL11032916 0.79 VCAM1 (0.51) VCAM1TSHRTDP1ALDH1A1HSD17B10
SCHEMBL6305 0.78 VCAM1 (0.50) VCAM1TSHRTDP1ALDH1A1PIN1
SCHEMBL10980919 0.78 TSHR (0.62) VCAM1TSHRTDP1ALDH1A1HSD17B10
SCHEMBL2913158 0.76 VCAM1 (0.57) VCAM1TSHRTDP1ALDH1A1MAPT
SCHEMBL2476425 0.76 VCAM1 (0.61) VCAM1TSHRTDP1ALDH1A1MAPT
SCHEMBL28011450 0.75 VCAM1 (0.44) VCAM1TSHRTDP1ALDH1A1HSD17B10
SCHEMBL7514813 0.75 ALDH1A1 (0.56) VCAM1TSHRTDP1ALDH1A1HSD17B10
SCHEMBL29702010 0.75 ALDH1A1 (0.56) VCAM1TSHRTDP1ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117326949-A Preparation method of 2, 4-dichloro-3-nitrobenzoic acid 清源创新实验室 2024-01-02 CN claimed
CN-117326949-A Preparation method of 2, 4-dichloro-3-nitrobenzoic acid 清源创新实验室 2024-01-02 CN disclosed