SCHEMBL30729607

SCHEMBL30729607

C[Si](C)(C)CCOCn1ccc2c(F)c(Br)nc(Cl)c21

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 4/20 0.39
DUT P33316 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30729613 0.86 DGAT1 (0.41) DGAT1
SCHEMBL27308814 0.86 DGAT1 (0.41) DGAT1
SCHEMBL25199720 0.78 DGAT1 (0.34) DGAT1DUT
SCHEMBL23292002 0.78 DGAT1 (0.40) DGAT1
SCHEMBL30467424 0.78 DGAT1 (0.38) DGAT1
SCHEMBL21685421 0.78 DGAT1 (0.38) DGAT1
SCHEMBL25643070 0.75 DGAT1 (0.39) DGAT1
SCHEMBL27657190 0.75 DGAT1 (0.37) DGAT1
SCHEMBL17902171 0.75 DGAT1 (0.36) DGAT1DUT
SCHEMBL27308866 0.74 NPC1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024025896-A2 PROTEIN KINASE C (PKC) THETA INHIBITOR COMPOUNDS EVOMMUNE, INC. (US) 2024-02-01 WO disclosed