Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 4/20 | 0.43 |
| ▸ | PNP | P00491 | 2/20 | 0.42 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 4/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.37 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218669 | 0.97 | MGMT (0.45) | MGMTPNPGDACYP1A2DPP4 | |
| Bromide SCHEMBL8165615 | 0.96 | MGMT (0.44) | MGMTPNPGDACYP1A2DPP4 | |
| SCHEMBL6821773 | 0.84 | PNP (0.45) | MGMTPNPGDACYP1A2DPP4 | |
| SCHEMBL28559768 | 0.83 | MGMT (0.41) | MGMTPNPGDACYP1A2DPP4 | |
| SCHEMBL5694191 | 0.82 | NPC1 (0.51) | MGMTPNPCYP1A2CDK2CDK1 | |
| SCHEMBL453204 | 0.82 | CYP1A2 (0.41) | MGMTPNPGDACYP1A2DPP4 | |
| SCHEMBL9710360 | 0.81 | PIN1 (0.68) | MGMTCYP1A2CDK2CDK1CCNB1 | |
| Acetic Acid SCHEMBL5323943 | 0.81 | MGMT (0.44) | MGMTPNPGDACYP1A2DPP4 | |
| SCHEMBL8843878 | 0.80 | PDE4A (0.43) | MGMTPNPCDK2CDK1CCNB1 | |
| SCHEMBL1740468 | 0.79 | PNP (0.40) | MGMTPNPCYP1A2CDK2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973886-A2 | METHOD AND CONJUGATE FOR TREATING $i(H. PYLORI) INFECTION | AVI BioPharm, Inc. (US) | 2000-01-26 | — | — | EP | disclosed |
| EP-0966303-A2 | POLYPEPTIDE CONJUGATES FOR TRANSPORTING SUBSTANCES ACROSS CELL MEMBRANES | ANTIVIRALS INC. (US) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998032467-A2 | METHOD AND CONJUGATE FOR TREATING H. PYLORI INFECTION | ANTIVIRALS, INC. (US) | 1998-07-30 | — | — | WO | disclosed |
| WO-1997040854-A2 | POLYPEPTIDE CONJUGATES FOR TRANSPORTING SUBSTANCES ACROSS CELL MEMBRANES | ANTIVIRALS INC. (US) | 1997-11-06 | — | — | WO | disclosed |