Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 3/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843867 | 0.83 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL5694071 | 0.83 | KMT2A (0.41) | ADORA2AKDM4EGAA | |
| SCHEMBL16401834 | 0.81 | FKBP1A (0.42) | — | |
| SCHEMBL218666 | 0.81 | GDA (0.34) | MGMTPDE4APDE4BPDE4CPDE4D | |
| Bromide SCHEMBL8165610 | 0.80 | GDA (0.33) | MGMTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3072987 | 0.80 | MGMT (0.45) | MGMTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6821768 | 0.79 | GDA (0.39) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL5347861 | 0.79 | XDH (0.42) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL453202 | 0.77 | GDA (0.32) | ADORA2AADORA2B | |
| SCHEMBL2940012 | 0.75 | KDM4E (0.46) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790843-B2 | Cypin polypeptide and fragments thereof | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2010-09-07 | — | — | US | disclosed |
| US-20080182970-A1 | Using cypin in assays, diagnostics and treatment of cognitive disorders | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2008-07-31 | — | — | US | disclosed |
| US-7338769-B2 | Methods for identifying agonists of cypin | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2008-03-04 | — | — | US | disclosed |
| US-20050214822-A1 | Using cypin in assays, diagnostics and treatment of cognitive disorders | RUTGERS, THE STATE UNIVERSITY OF NEV | 2005-09-29 | — | — | US | disclosed |