Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 5/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27097024 | 1.00 | MRGPRX4 (0.40) | MRGPRX4SYKHPGDTSHRALDH1A1 | |
| SCHEMBL23538009 | 0.83 | HPGD (0.40) | MRGPRX4SYKHPGDTSHRALDH1A1 | |
| SCHEMBL27097014 | 0.78 | MAPT (0.51) | HPGDALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL23537751 | 0.75 | HPGD (0.49) | MRGPRX4SYKHPGDTSHRALDH1A1 | |
| SCHEMBL2986980 | 0.74 | EGFR (0.44) | MRGPRX4SYKHPGDTSHRALDH1A1 | |
| SCHEMBL23537705 | 0.73 | L3MBTL1 (0.51) | MRGPRX4SYKHPGDTSHRALDH1A1 | |
| SCHEMBL3320471 | 0.72 | MAOB (0.56) | MRGPRX4HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31193398 | 0.72 | MAOB (0.56) | MRGPRX4HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL34472753 | 0.70 | CYP3A4 (0.46) | MRGPRX4SYKHPGDTSHRALDH1A1 | |
| SCHEMBL27897847 | 0.70 | CYP3A4 (0.46) | MRGPRX4SYKHPGDTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026056-A2 | HETEROARYL COMPOUNDS AS EGFR INHIBITORS AND THEIR USES | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-02-01 | — | — | WO | disclosed |