Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CTSD | P07339 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30730401 | 0.87 | HTR1A (0.40) | HTR1ADRD2DRD4IRAK4TGFBR1 | |
| SCHEMBL30730264 | 0.82 | TRPV3 (0.40) | HTR1ADRD2DRD4CNR2 | |
| SCHEMBL27396457 | 0.79 | CACNA1B (0.37) | HTR1ADRD2DRD4PDE4DPDE4B | |
| SCHEMBL27326665 | 0.74 | CNR2 (0.46) | HTR1ADRD2DRD4CNR2 | |
| SCHEMBL30730115 | 0.74 | CNR2 (0.46) | HTR1ADRD2DRD4CNR2 | |
| SCHEMBL27314506 | 0.74 | LRRK2 (0.34) | HTR1ADRD2DRD4F2PLG | |
| SCHEMBL27316765 | 0.71 | CACNA1B (0.39) | HTR1ADRD2DRD4IRAK4TGFBR1 | |
| SCHEMBL27394813 | 0.70 | LRRK2 (0.34) | HTR1ADRD2DRD4F2PLG | |
| SCHEMBL30730250 | 0.66 | TRPV3 (0.38) | IRAK4 | |
| SCHEMBL27938280 | 0.66 | KDM4E (0.42) | ADORA2APDE4DPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562015-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026481-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |