SCHEMBL30730264

SCHEMBL30730264

NNC(=O)Cc1nc(C2CCOCC2)ccc1F

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TRPV3 Q8NET8 11/20 0.40
MAPK1 P28482 5/20 0.39
HTR1A P08908 2/20 0.38
DRD2 P14416 2/20 0.38
DRD4 P21917 2/20 0.38
CNR2 P34972 1/20 0.37
KCNH2 Q12809 1/20 0.36
AOC3 Q16853 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30730299 0.82 HTR1A (0.38) HTR1ADRD2DRD4CNR2
SCHEMBL30730250 0.78 TRPV3 (0.38) TRPV3MAPK1
SCHEMBL30730115 0.77 CNR2 (0.46) MAPK1HTR1ADRD2DRD4CNR2
SCHEMBL27326665 0.77 CNR2 (0.46) MAPK1HTR1ADRD2DRD4CNR2
SCHEMBL12616252 0.70 TRPV3 (0.59) TRPV3
SCHEMBL12539294 0.69 TRPV3 (0.81) TRPV3
SCHEMBL30730401 0.68 HTR1A (0.40) HTR1ADRD2DRD4CNR2KCNH2
SCHEMBL2371040 0.65 PIK3CD (0.43) MAPK1HTR1ADRD2DRD4CNR2
SCHEMBL22899862 0.64 CHRNA7 (0.38) TRPV3MAPK1HTR1ADRD2DRD4
SCHEMBL30308868 0.64 MAP2K3 (0.46) MAPK1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4562015-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME Cedilla Therapeutics, Inc. (US) 2025-06-04 EP disclosed
WO-2024026481-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed