Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | FABP7 | O15540 | 1/20 | 0.33 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13199166 | 0.79 | TSHR (0.46) | TSHRKDM4EPOLBNPSR1ACSS2 | |
| SCHEMBL13199136 | 0.78 | TSHR (0.49) | TSHRKDM4EPOLBNPSR1ACSS2 | |
| SCHEMBL30730411 | 0.75 | LIPE (0.46) | PIK3CAPIK3CDBRD4TSHRKDM4E | |
| SCHEMBL1171941 | 0.74 | ACSS2 (0.48) | POLBNPSR1ACSS2MAPT | |
| SCHEMBL16595716 | 0.74 | MAPT (0.47) | TSHRKDM4ENPSR1MEN1MAPT | |
| SCHEMBL5003336 | 0.73 | NPSR1 (0.47) | TSHRPOLBNPSR1ACSS2MAPT | |
| SCHEMBL17583195 | 0.73 | NPSR1 (0.51) | TSHRKDM4EPOLBNPSR1ACSS2 | |
| SCHEMBL12014193 | 0.73 | LMNA (0.45) | TSHRKDM4ENPSR1ACSS2MEN1 | |
| SCHEMBL2396473 | 0.72 | MAPT (0.50) | TSHRKDM4ENPSR1ACSS2MEN1 | |
| SCHEMBL31306426 | 0.72 | CA12 (0.55) | TSHRPOLBACSS2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562015-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026481-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |