Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22554205 | 1.00 | TBK1 (0.49) | TBK1ALDH1A1HPGDCYP11B2CCNC | |
| SCHEMBL22553745 | 0.93 | TBK1 (0.45) | TBK1ALDH1A1HPGDCYP11B2CDK9 | |
| SCHEMBL22553975 | 0.87 | TBK1 (0.44) | TBK1ALDH1A1HPGDCYP11B2NUDT1 | |
| SCHEMBL30730801 | 0.87 | TBK1 (0.44) | TBK1ALDH1A1HPGDCYP11B2NUDT1 | |
| SCHEMBL30731110 | 0.86 | NUDT1 (0.46) | TBK1ALDH1A1CYP11B2NUDT1NPC1 | |
| SCHEMBL22554106 | 0.86 | TBK1 (0.39) | TBK1ALDH1A1HPGDCYP11B2CCNC | |
| SCHEMBL30731170 | 0.86 | TBK1 (0.39) | TBK1ALDH1A1HPGDCYP11B2CCNC | |
| SCHEMBL22553938 | 0.85 | NUDT1 (0.43) | TBK1ALDH1A1HPGDCYP11B2NUDT1 | |
| SCHEMBL22554135 | 0.85 | NUDT1 (0.57) | TBK1ALDH1A1CYP11B2CCNT1CDK9 | |
| SCHEMBL30731117 | 0.85 | NUDT1 (0.43) | TBK1ALDH1A1HPGDCYP11B2NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | claimed |
| US-11919902-B2 | Aryl-bipyridine amine derivatives as phosphatidylinositol phosphate kinase inhibitors | HIBERCELL, INC. (US) | 2024-03-05 | — | — | US | disclosed |
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11919902-B2 | Aryl-bipyridine amine derivatives as phosphatidylinositol phosphate kinase inhibitors | PIP5K1A, PIP5K1B, PIP5K1C | TBK1 714/4885ALDH1A1 4524/4885HPGD 3902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.