Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22553751 | 1.00 | TBK1 (0.41) | TBK1DGAT2SMN1; SMN2MAPTNPC1 | |
| SCHEMBL22553938 | 0.88 | NUDT1 (0.43) | TBK1DGAT2SMN1; SMN2MAPTNPC1 | |
| SCHEMBL30730826 | 0.88 | NUDT1 (0.43) | TBK1DGAT2SMN1; SMN2MAPTNPC1 | |
| SCHEMBL30731117 | 0.88 | NUDT1 (0.43) | TBK1DGAT2SMN1; SMN2MAPTNPC1 | |
| SCHEMBL22554042 | 0.85 | DGAT2 (0.40) | TBK1DGAT2SMN1; SMN2MAPTNPC1 | |
| SCHEMBL30730806 | 0.85 | DGAT2 (0.40) | TBK1DGAT2SMN1; SMN2MAPTNPC1 | |
| SCHEMBL22553861 | 0.82 | NUDT1 (0.41) | TBK1DGAT2SMN1; SMN2MAPTNPC1 | |
| SCHEMBL30777590 | 0.82 | NUDT1 (0.41) | TBK1DGAT2SMN1; SMN2MAPTNPC1 | |
| SCHEMBL22554168 | 0.82 | NUDT1 (0.41) | TBK1DGAT2SMN1; SMN2MAPTNPC1 | |
| SCHEMBL30730817 | 0.82 | NUDT1 (0.41) | TBK1DGAT2SMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | claimed |
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | disclosed |