Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CCNC | P24863 | 2/20 | 0.38 |
| ▸ | CDK8 | P49336 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
| ▸ | CD38 | P28907 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22553963 | 1.00 | PIP4K2A (0.46) | PIP4K2ASMN1; SMN2NPC1HTTCYP11B2 | |
| SCHEMBL22578369 | 0.84 | TGFBR1 (0.47) | MAPTTGFBR1ACVR1BACVR1CHEK1 | |
| SCHEMBL30730784 | 0.83 | CYP11B2 (0.41) | PIP4K2ASMN1; SMN2NPC1HTTCYP11B2 | |
| SCHEMBL22553817 | 0.83 | CYP11B2 (0.41) | PIP4K2ASMN1; SMN2NPC1HTTCYP11B2 | |
| SCHEMBL22553979 | 0.83 | BRD4 (0.48) | PIP4K2ANPC1CYP11B2CYP11B1CCNC | |
| SCHEMBL30730803 | 0.82 | SMN1; SMN2 (0.41) | PIP4K2ASMN1; SMN2NPC1HTTCYP11B2 | |
| SCHEMBL22553792 | 0.82 | SMN1; SMN2 (0.41) | PIP4K2ASMN1; SMN2NPC1HTTCYP11B2 | |
| SCHEMBL22553970 | 0.82 | CYP11B1 (0.41) | PIP4K2ASMN1; SMN2NPC1HTTCYP11B2 | |
| SCHEMBL22554228 | 0.82 | PIP4K2A (0.44) | PIP4K2ANPC1CYP11B2CYP11B1CCNC | |
| SCHEMBL22553945 | 0.80 | PIP4K2A (0.55) | PIP4K2ANPC1CYP11B2CYP11B1CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | claimed |
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | disclosed |