Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17422305 | 0.73 | LMNA (0.30) | LMNASMN1; SMN2 | |
| SCHEMBL3695226 | 0.71 | ADORA2A (0.34) | — | |
| SCHEMBL3915550 | 0.71 | TLR7 (0.34) | TLR7LMNASMN1; SMN2FBP1 | |
| SCHEMBL10514950 | 0.67 | LMNA (0.38) | TLR7CA12CA2CA9LMNA | |
| SCHEMBL7753780 | 0.67 | LMNA (0.52) | CA12CA2CA9LMNASMN1; SMN2 | |
| SCHEMBL24773616 | 0.66 | LMNA (0.43) | TLR7CA12CA2CA9LMNA | |
| SCHEMBL14019477 | 0.66 | TLR9 (0.33) | LMNASMN1; SMN2 | |
| SCHEMBL14767684 | 0.66 | TLR7 (0.43) | TLR7CA12CA2CA9LMNA | |
| SCHEMBL18067288 | 0.64 | LMNA (0.35) | TLR7CA12CA2CA9LMNA | |
| SCHEMBL11509596 | 0.64 | GLP1R (0.38) | TLR7CA12CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003756-A | Use of aromatic condensed-cyclic compounds as TREK-1 activators, pharmaceutical compositions containing same, analgesics | 华东师范大学 | 2023-11-07 | — | — | CN | disclosed |