Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 15/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12282686 | 0.73 | KDM4E (0.30) | — | |
| SCHEMBL12261685 | 0.73 | KDM4E (0.30) | — | |
| SCHEMBL10514950 | 0.71 | LMNA (0.38) | TLR7CA12CA2CA9LMNA | |
| SCHEMBL31139341 | 0.69 | MAPT (0.44) | TLR7LMNASMN1; SMN2 | |
| SCHEMBL11426170 | 0.67 | PDE10A (0.47) | TLR7LMNASMN1; SMN2 | |
| SCHEMBL30730952 | 0.66 | TLR7 (0.32) | TLR7CA12CA2CA9LMNA | |
| SCHEMBL11509596 | 0.64 | GLP1R (0.38) | TLR7CA12CA2CA9LMNA | |
| SCHEMBL18067288 | 0.64 | LMNA (0.35) | TLR7CA12CA2CA9LMNA | |
| SCHEMBL31713043 | 0.64 | PDPK1 (0.56) | TLR7LMNA | |
| SCHEMBL3915555 | 0.64 | PDPK1 (0.56) | TLR7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2573559-A1 | Modulation of chemosensory receptors and ligands associated | Senomyx, Inc. (US) | 2013-03-27 | — | — | EP | disclosed |
| EP-2568287-A2 | Modulation of chemosensory receptors and ligands associated | Senomyx, Inc. (US) | 2013-03-13 | — | — | EP | disclosed |