Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.51 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13443057 | 0.79 | HCRTR1 (0.67) | KMT2AHTT | |
| SCHEMBL14082503 | 0.78 | ROCK2 (0.74) | HPGDSMAPK1SCN2ASCN10AKMT2A | |
| SCHEMBL354041 | 0.76 | TSHR (0.76) | HPGDSMAPK1KMT2ASMN1; SMN2HDAC1 | |
| SCHEMBL246648 | 0.75 | MMP13 (0.74) | MAPK1HDAC1NAMPTRAB9AROCK2 | |
| SCHEMBL6316553 | 0.75 | ALDH1A1 (0.66) | MAPK1KMT2ASMN1; SMN2HTTNAMPT | |
| SCHEMBL22573405 | 0.75 | HTT (0.56) | HPGDSMAPK1KMT2ASMN1; SMN2HTT | |
| Iodide SCHEMBL15903217 | 0.75 | TSHR (0.74) | HPGDSMAPK1KMT2ASMN1; SMN2HDAC1 | |
| SCHEMBL12190863 | 0.74 | SCN2A (0.62) | MAPK1SCN2ASCN10AKMT2ASMN1; SMN2 | |
| SCHEMBL2984197 | 0.74 | NAMPT (0.72) | MAPK1KMT2AHTTNAMPTRAB9A | |
| Hydrochloric Acid SCHEMBL11508166 | 0.73 | TSHR (0.72) | HPGDSMAPK1KMT2ASMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | disclosed |