Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CLK1 | P49759 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28652788 | 0.80 | KMT2A (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL30731280 | 0.79 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1CLK1 | |
| SCHEMBL29405880 | 0.76 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL28652940 | 0.76 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL29690517 | 0.73 | LMNA (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1SENP7 | |
| SCHEMBL8314254 | 0.70 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2ALDH1A1CLK1 | |
| SCHEMBL334252 | 0.70 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2ALDH1A1CLK1 | |
| SCHEMBL16655557 | 0.69 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1CLK1 | |
| SCHEMBL10533598 | 0.68 | KMT2A (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1CLK1 | |
| SCHEMBL16666137 | 0.68 | CASP3 (0.59) | NPC1RAB9ASMN1; SMN2ALDH1A1CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605349-B | Synthesis method of photocatalytic alkyl substituted benzothiazole derivative | 浙江工业大学 | 2024-01-30 | — | — | CN | disclosed |