Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26924969 | 1.00 | CYP2D6 (0.39) | CYP2D6CYP3A4USP2ALDH1A1MAPK1 | |
| SCHEMBL30731789 | 0.89 | GPR119 (0.41) | CYP3A4USP2MAPK1OPRD1OPRK1 | |
| SCHEMBL26924752 | 0.89 | GPR119 (0.41) | CYP3A4USP2MAPK1OPRD1OPRK1 | |
| SCHEMBL26925663 | 0.88 | NSD2 (0.39) | ALDH1A1NSD2TLR9TLR7IDO1 | |
| SCHEMBL34461203 | 0.87 | PRMT5 (0.39) | OPRD1OPRK1TLR9TLR7GPR119 | |
| SCHEMBL26925586 | 0.86 | OPRD1 (0.39) | OPRD1OPRK1TLR9TLR7GPR119 | |
| SCHEMBL30731996 | 0.86 | OPRD1 (0.39) | OPRD1OPRK1TLR9TLR7GPR119 | |
| SCHEMBL26925336 | 0.86 | GPR119 (0.38) | TLR9TLR7GPR119YAP1 | |
| SCHEMBL30706160 | 0.86 | GPR119 (0.38) | TLR9TLR7GPR119YAP1 | |
| SCHEMBL31554749 | 0.85 | YAP1 (0.44) | TLR9TLR7GPR119YAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536650-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| CN-119317623-A | Tricyclic quinolone BCL6 bifunctional degradation agents | 树线生物科学公司 | 2025-01-14 | — | — | CN | disclosed |
| WO-2023240038-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-12-14 | — | — | WO | disclosed |