SCHEMBL10205403

SCHEMBL10205403

Cc1cnccc1-c1cccnc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.61
CYP2A6 P11509 11/20 0.59
CYP3A4 P08684 6/20 0.59
CYP2E1 P05181 4/20 0.59
CYP2C9 P11712 4/20 0.59
CYP2B6 P20813 3/20 0.59
CYP2D6 P10635 3/20 0.59
CYP2C19 P33261 3/20 0.59
ALDH1A1 P00352 2/20 0.56
CYP1A2 P05177 2/20 0.56
GRM4 Q14833 1/20 0.50
KDM4E B2RXH2 1/20 0.48
LMNA P02545 1/20 0.48
TP53 P04637 1/20 0.48
MAPT P10636 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
HTT P42858 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HSD17B10 Q99714 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9169968 0.85 GRM4 (0.60) CYP19A1CYP2A6CYP3A4CYP2E1CYP2C9
SCHEMBL31258556 0.85 GRM4 (0.60) CYP19A1CYP2A6CYP3A4CYP2E1CYP2C9
SCHEMBL3752648 0.83 KDM4E (0.61) CYP19A1CYP2A6CYP3A4CYP2E1CYP2C9
SCHEMBL12258295 0.83 CYP2A6 (0.59) CYP19A1CYP2A6CYP3A4CYP2E1CYP2C9
SCHEMBL21202128 0.82 GRM4 (0.51) CYP19A1GRM4CCNCCDK8CYP11B1
SCHEMBL29394740 0.81 CYP2A6 (0.61) CYP2A6CYP3A4CYP2E1CYP2C9CYP2B6
SCHEMBL18174778 0.81 CYP19A1 (0.45) CYP19A1CYP2A6CYP3A4CYP2E1CYP2C9
SCHEMBL30395768 0.80 GRM4 (0.50) CYP19A1CYP2A6CYP3A4CYP2E1CYP2C9
SCHEMBL12258294 0.80 GRM4 (0.50) CYP19A1CYP2A6CYP3A4CYP2E1CYP2C9
SCHEMBL12915119 0.80 CYP2A6 (0.56) CYP19A1CYP2A6CYP3A4CYP2E1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11818932-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-14 US disclosed
EP-4225006-A2 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2023-08-09 EP disclosed
US-11706973-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-18 US disclosed
US-11696496-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-04 US disclosed
US-11678498-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-13 US disclosed
US-11653563-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-16 US disclosed
US-11617290-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-03-28 US disclosed
US-11329230-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2022-05-10 US disclosed
US-11316117-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-26 US disclosed
US-20210336144-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-10-28 US disclosed
US-20170054085-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-23 US disclosed
US-20170054085-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-23 US disclosed
US-20160322579-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-11-03 US disclosed
US-20160293845-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-06 US disclosed
US-20160293848-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-06 US disclosed
US-20160285011-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-09-29 US disclosed
US-20150236271-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME DOOSAN CORPORATION (KR) 2015-08-20 US disclosed
US-20130105769-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2013-05-02 US disclosed
US-20130105769-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2013-05-02 US disclosed
US-8101774-B2 Ester derivatives and medicinal use thereof JAPAN TOBACCO INC. (JP) 2012-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11329230-B2 Organic light-emitting device EML4, SUN2, TRPA1 CYP19A1 1341/4885CYP2A6 1675/4885CYP3A4 247/4885
US-20130105769-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNT1, CCNE2 CYP19A1 97/4885CYP2A6 1313/4885CYP3A4 612/4885
US-11706973-B2 Condensed cyclic compound and organic light-emitting device including the same C1S, CCNT1, C9 CYP19A1 174/4885CYP2A6 213/4885CYP3A4 1569/4885
US-20160293848-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 CYP19A1 88/4885CYP2A6 2249/4885CYP3A4 979/4885
US-20160285011-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME CCNA1, CCNT1, CCNE2 CYP19A1 112/4885CYP2A6 1507/4885CYP3A4 1129/4885
US-11316117-B2 Organometallic compound and organic light-emitting device including the same OCIAD1, L3MBTL1, OCIAD2 CYP19A1 562/4885CYP2A6 2875/4885CYP3A4 1084/4885
US-20150236271-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME OR10J3, VDAC1, VDAC2 CYP19A1 2117/4885CYP2A6 3910/4885CYP3A4 1313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.