Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3073309 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL3083536 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL30658808 | 0.89 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL14492355 | 0.78 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL9489089 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL10437609 | 0.74 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL10437611 | 0.74 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL10437607 | 0.74 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL30658789 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL7158584 | 0.73 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100228038-A1 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-09-09 | — | — | US | disclosed |
| US-7667055-B2 | Processes for the production of polycyclic fused ring compounds | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-02-23 | — | — | US | disclosed |
| US-7550608-B2 | Processes for the preparation of docetaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-06-23 | — | — | US | disclosed |
| EP-1919926-A2 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS | Florida State University Research Foundation, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| US-7358378-B2 | Processes for the preparation of paclitaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2008-04-15 | — | — | US | disclosed |
| EP-1893594-A2 | PROCESSES FOR THE PREPARATION OF PACLITAXEL | Florida State University Research Foundation, Inc. (US) | 2008-03-05 | — | — | EP | disclosed |
| EP-1891033-A2 | PROCESSES FOR THE PREPARATION OF DOCETAXEL | Florida State University Research Foundation, Inc. (US) | 2008-02-27 | — | — | EP | disclosed |
| EP-1888521-A2 | RESOLUTION OF ENANTIOMERIC MIXTURES OF ß-LACTAMS | Florida State University Research Foundation, Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006135656-A2 | PROCESSES FOR THE PREPARATION OF PACLITAXEL | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-21 | — | — | WO | disclosed |
| WO-2006135692-A2 | PROCESSES FOR THE PREPARATION OF DOCETAXEL | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-21 | — | — | WO | disclosed |
| WO-2006135655-A2 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-21 | — | — | WO | disclosed |
| WO-2006135669-A2 | RESOLUTION OF ENANTIOMERIC MIXTURES OF β-LACTAMS | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-21 | — | — | WO | disclosed |
| US-20060281934-A1 | Processes for the production of polycyclic fused ring compounds | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | US | disclosed |
| US-20060281933-A1 | Processes for the preparation of paclitaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | US | disclosed |
| US-20060281918-A1 | Resolution of enantiomeric mixtures of beta-lactams | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | US | disclosed |
| US-20060281932-A1 | Processes for the preparation of docetaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281934-A1 | Processes for the production of polycyclic fused ring compounds | COASY, PARG, PIN4 | ALDH1A1 4039/4885KDM4E 2362/4885HPGD 2817/4885 |
| US-20060281918-A1 | Resolution of enantiomeric mixtures of beta-lactams | C9, PEPD, PTMA | ALDH1A1 1937/4885KDM4E 3393/4885HPGD 1617/4885 |
| US-20060281933-A1 | Processes for the preparation of paclitaxel | PDCD10, PDS5B, CASP10 | ALDH1A1 1118/4885KDM4E 1426/4885HPGD 1967/4885 |
| US-20100228038-A1 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS | COASY, PARG, PIN4 | ALDH1A1 4039/4885KDM4E 2362/4885HPGD 2817/4885 |
| US-20060281932-A1 | Processes for the preparation of docetaxel | PDCD10, PDS5B, DHCR7 | ALDH1A1 954/4885KDM4E 868/4885HPGD 939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.