Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7097156 | 0.82 | ALDH1A1 (0.58) | ALDH1A1LTC4STSHRNPC1RAB9A | |
| SCHEMBL6229768 | 0.81 | ALDH1A1 (0.57) | ALDH1A1LTC4SKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL6805540 | 0.75 | ALDH1A1 (0.45) | ALDH1A1LTC4STSHRSMN1; SMN2NPC1 | |
| SCHEMBL13885949 | 0.72 | ALDH1A1 (0.68) | ALDH1A1LTC4STSHRSMN1; SMN2NPC1 | |
| SCHEMBL6953144 | 0.71 | ALDH1A1 (0.62) | ALDH1A1LTC4SKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL6907332 | 0.70 | ALDH1A1 (0.52) | ALDH1A1LTC4SSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7224530 | 0.69 | LTC4S (0.87) | ALDH1A1LTC4SKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL7220245 | 0.68 | LTC4S (0.79) | ALDH1A1LTC4SKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL7579004 | 0.68 | ALDH1A1 (0.49) | ALDH1A1LTC4STSHRSMN1; SMN2NPC1 | |
| SCHEMBL7624466 | 0.67 | ALDH1A1 (1.00) | ALDH1A1LTC4SKDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4361273-A1 | ANTI-CTLA-4 ANTIBODY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-05-01 | — | — | EP | disclosed |
| US-20240043515-A1 | HETERODIMER FC POLYPEPTIDE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-02-08 | — | — | US | disclosed |
| US-20230416371-A1 | HETERODIMER FC POLYPEPTIDE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-12-28 | — | — | US | disclosed |