Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.57 |
| ▸ | FPR3 | P25089 | 1/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6229768 | 0.99 | ALDH1A1 (0.57) | ALDH1A1LTC4SFPR3FPR2ACHE | |
| SCHEMBL30733352 | 0.82 | ALDH1A1 (0.50) | ALDH1A1LTC4SFPR3FPR2TSHR | |
| SCHEMBL2320244 | 0.79 | NMT1 (0.51) | FPR3FPR2ACHETSHRNPC1 | |
| SCHEMBL13885949 | 0.79 | ALDH1A1 (0.68) | ALDH1A1LTC4STSHRSSTR4POLB | |
| SCHEMBL1256229 | 0.78 | NMT1 (0.53) | FPR3FPR2ACHE | |
| SCHEMBL6953144 | 0.78 | ALDH1A1 (0.62) | ALDH1A1LTC4SPOLBMAPTNPC1 | |
| SCHEMBL7224530 | 0.76 | LTC4S (0.87) | ALDH1A1LTC4STSHRSSTR4POLB | |
| SCHEMBL29355043 | 0.74 | ALDH1A1 (1.00) | ALDH1A1LTC4SPOLBMAPTNPC1 | |
| SCHEMBL7624466 | 0.74 | ALDH1A1 (1.00) | ALDH1A1LTC4SPOLBMAPTNPC1 | |
| SCHEMBL12190202 | 0.74 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194427-B1 | THIOPHENE-ETHYL THIOUREA COMPOUNDS AND USE IN THE TREATMENT OF HIV | PARKER HUGHES INST (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6124324-A | AN ENZYME INHIBITOR OF REVERSE TRANSCRIPTASE FOR THE TREATMENT OF HIV INFECTION, INCLUDING MUTANT, DRUG-SENSITIVE, DRUG-RESISTANT, AND MULTI-DRUG RESISTANT STRAINS OF HIV | HUGHES INSTITUTE (US) | 2000-09-26 | — | — | US | disclosed |