SCHEMBL30733426

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30733411	0.94	SIGMAR1 (0.46)	HDAC1HDAC6SIGMAR1TSHRTP53
	SCHEMBL30733432	0.91	HDAC1 (0.47)	HDAC1HDAC6SIGMAR1TSHRTP53
	SCHEMBL25274233	0.86	MEN1 (0.51)	HDAC1HDAC6TSHRALDH1A1MEN1
	SCHEMBL25231257	0.86	MEN1 (0.43)	HDAC1HDAC6SIGMAR1TSHRALDH1A1
	SCHEMBL30733430	0.86	TSHR (0.49)	HDAC1HDAC6TSHRALDH1A1HDAC8
	SCHEMBL26969719	0.85	TSHR (0.48)	HDAC1HDAC6TSHRALDH1A1HDAC8
	SCHEMBL25237332	0.83	MEN1 (0.47)	HDAC1HDAC6TSHRALDH1A1MEN1
	SCHEMBL25274492	0.79	HDAC1 (0.57)	HDAC1HDAC6TSHRCYP2C19HDAC8
	SCHEMBL30733402	0.78	HDAC1 (0.48)	HDAC1HDAC6SIGMAR1TSHRTP53
	SCHEMBL30733404	0.78	HDAC1 (0.43)	HDAC1HDAC6SIGMAR1TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.