Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 15/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 13/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 13/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 10/20 | 0.49 |
| ▸ | LMNA | P02545 | 9/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.48 |
| ▸ | USP2 | O75604 | 8/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30734233 | 0.89 | ACHE (0.55) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL30734231 | 0.89 | CYP3A4 (0.52) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL30734187 | 0.89 | ACHE (0.53) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL30734169 | 0.83 | CYP3A4 (0.54) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL30734142 | 0.83 | MAP4K4 (0.44) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL30734171 | 0.83 | CYP1A2 (0.62) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL30734129 | 0.81 | ACHE (0.55) | ALDH1A1MEN1KMT2AKDM4ECYP3A4 | |
| SCHEMBL30734206 | 0.80 | CYP3A4 (0.50) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL30734203 | 0.80 | ACHE (0.56) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL31745183 | 0.79 | MEN1 (0.54) | ALDH1A1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382301-A1 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | UNIV ARIZONA (US) | 2025-12-18 | — | — | US | disclosed |
| EP-4543888-A1 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | Arizona Board of Regents on behalf of The University of Arizona (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023250083-A1 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2023-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250382301-A1 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | CLK2, CLK3, CLK1 | ALDH1A1 4568/4885MEN1 407/4885KMT2A 2060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.