Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA7 | P43166 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.45 |
| ▸ | GHSR | Q92847 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30734308 | 1.00 | ESR1 (0.51) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL27276906 | 1.00 | ESR1 (0.51) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL27276905 | 0.84 | ESR1 (0.51) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL1567179 | 0.83 | CHRM3 (0.58) | TRPV1CHRM3 | |
| SCHEMBL25142600 | 0.83 | CHRM3 (0.58) | TRPV1CHRM3 | |
| SCHEMBL30710294 | 0.83 | NR1H2 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30710500 | 0.82 | TRPM8 (0.41) | TRPV1MEN1KMT2A | |
| SCHEMBL29560706 | 0.82 | TRPV1 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30710404 | 0.80 | LMNA (0.42) | ESR2TRPV1LMNAGHSRTSHR | |
| SCHEMBL30710250 | 0.80 | LMNA (0.42) | ESR2TRPV1LMNAGHSRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250399-A1 | TREX1 INHIBITORS AND USES THEREOF | TEMPEST THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |