Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16059989 | 0.84 | ALDH1A1 (0.44) | GAANPC1ALDH1A1CYP3A4MAPT | |
| SCHEMBL1822491 | 0.78 | GAA (0.47) | GAANPC1HTR2CHTR1AHTR1D | |
| SCHEMBL2826069 | 0.78 | MAPT (0.55) | GAANPC1HTR2CHTR1AHTR1D | |
| SCHEMBL171097 | 0.77 | GAA (0.40) | GAANPC1HTR2CHTR1AHTR1D | |
| SCHEMBL30735735 | 0.74 | ALDH1A1 (0.38) | GAANPC1HTR2CTAAR1ALDH1A1 | |
| SCHEMBL6776267 | 0.74 | ALDH1A1 (0.42) | GAANPC1HTR2CALDH1A1CYP3A4 | |
| SCHEMBL11257446 | 0.74 | ALDH1A1 (0.42) | GAANPC1HTR2CTAAR1ALDH1A1 | |
| SCHEMBL26091619 | 0.74 | NPC1 (0.42) | GAANPC1HTR2CHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL6475701 | 0.74 | ATP4A (0.44) | GAANPC1HTR2CHTR1AHTR1D | |
| SCHEMBL10118361 | 0.73 | MAPT (0.42) | GAANPC1HTR2CHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543881-A1 | COMPOUNDS AND METHOD FOR PKMYT1 INHIBITION | Engine Biosciences Pte. Ltd. (SG) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023249563-A1 | COMPOUNDS AND METHOD FOR PKMYT1 INHIBITION | ENGINE BIOSCIENCES PTE. LTD. (SG) | 2023-12-28 | — | — | WO | disclosed |