Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.58 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.54 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.54 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | FNTA | P49354 | 3/20 | 0.50 |
| ▸ | FNTB | P49356 | 3/20 | 0.50 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30736199 | 0.96 | OPRM1 (0.57) | OPRM1OPRD1NMUR2NMUR1BDKRB2 | |
| SCHEMBL30736308 | 0.91 | OPRD1 (0.62) | OPRM1OPRD1NMUR2NMUR1BDKRB2 | |
| SCHEMBL31596868 | 0.89 | OPRM1 (0.64) | OPRM1OPRD1BDKRB2OPRK1SLC6A2 | |
| SCHEMBL31596986 | 0.89 | OPRM1 (0.64) | OPRM1OPRD1BDKRB2OPRK1SLC6A2 | |
| SCHEMBL30736126 | 0.87 | OPRD1 (0.61) | OPRM1OPRD1NMUR2NMUR1BDKRB2 | |
| SCHEMBL30159031 | 0.87 | NMUR2 (0.57) | OPRM1OPRD1NMUR2NMUR1 | |
| SCHEMBL31612385 | 0.86 | OPRM1 (0.61) | OPRM1OPRD1BDKRB2OPRK1 | |
| SCHEMBL30736117 | 0.85 | FNTA (0.64) | FNTAFNTBPGGT1B | |
| SCHEMBL30401696 | 0.85 | BDKRB2 (0.58) | OPRM1OPRD1BDKRB2OPRK1F2 | |
| SCHEMBL34461924 | 0.83 | OPRD1 (0.67) | OPRM1OPRD1NMUR2NMUR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247999-A1 | PEPTIDIC PAIN MODULATORS AND METHODS FOR PRODUCING AND USING THE SAME | MAINLINE BIOSCIENCES (SHANGHAI) CO., LTD. (CN) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247999-A1 | PEPTIDIC PAIN MODULATORS AND METHODS FOR PRODUCING AND USING THE SAME | MAINLINE BIOSCIENCES (SHANGHAI) CO., LTD. (CN) | 2023-12-28 | — | — | WO | disclosed |