Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26986481 | 0.86 | KDM4E (0.45) | KMT2AALDH1A1HPGDRAB9AKDM4E | |
| SCHEMBL27135713 | 0.86 | KDM4E (0.45) | KMT2AALDH1A1HPGDRAB9AKDM4E | |
| SCHEMBL30025905 | 0.85 | KMT2A (0.53) | KMT2AABL1RIN1ALDH1A1HPGD | |
| SCHEMBL27157300 | 0.85 | KMT2A (0.53) | KMT2AABL1RIN1ALDH1A1HPGD | |
| SCHEMBL27157330 | 0.80 | KMT2A (0.62) | KMT2AABL1RIN1ALDH1A1HPGD | |
| SCHEMBL30217976 | 0.77 | ALDH1A1 (0.45) | ALDH1A1RAB9AUSP30MAPTHDAC4 | |
| SCHEMBL29119864 | 0.77 | ALDH1A1 (0.45) | ALDH1A1RAB9AUSP30MAPTHDAC4 | |
| SCHEMBL29119866 | 0.77 | ALDH1A1 (0.45) | ALDH1A1RAB9AUSP30MAPTHDAC4 | |
| SCHEMBL30218491 | 0.77 | ALDH1A1 (0.45) | ALDH1A1RAB9AUSP30MAPTHDAC4 | |
| SCHEMBL28681115 | 0.76 | CHEK2 (0.51) | ALDH1A1USP30MAPTHPGDSGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551218-A2 | POTENT AND SELECTIVE IRREVERSIBLE INHIBITORS OF IRAK1 | Dana-Farber Cancer Institute, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024011116-A2 | POTENT AND SELECTIVE IRREVERSIBLE INHIBITORS OF IRAK1 | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-01-11 | — | — | WO | disclosed |