SCHEMBL30736652

SCHEMBL30736652

CCOC(=O)c1cc(C(F)(F)F)ccc1C1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.54
POLB P06746 2/20 0.54
ALDH1A1 P00352 2/20 0.52
MEN1 O00255 1/20 0.52
LMNA P02545 1/20 0.52
GAA P10253 1/20 0.52
KMT2A Q03164 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
HPGD P15428 2/20 0.50
KDM4E B2RXH2 1/20 0.50
GPR119 Q8TDV5 4/20 0.47
GUCY1A1 Q02108 1/20 0.46
GUCY1B1 Q02153 1/20 0.46
TGFBR1 P36897 1/20 0.45
NOTCH1 P46531 1/20 0.45
MAPT P10636 2/20 0.45
STS P08842 1/20 0.45
P2RY14 Q15391 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26118196 0.85 TRPV1 (0.53) POLBMEN1KMT2AKDM4EGPR119
SCHEMBL17305372 0.83 GPR119 (0.45) TP53POLBALDH1A1MEN1LMNA
SCHEMBL17305229 0.82 TGFBR1 (0.43) TP53POLBALDH1A1MEN1LMNA
SCHEMBL19078350 0.82 STS (0.46) TP53POLBALDH1A1MEN1KMT2A
SCHEMBL17305159 0.82 STS (0.50) POLBKDM4EGPR119TGFBR1MAPT
SCHEMBL19087908 0.81 TGFBR1 (0.47) TP53POLBSMN1; SMN2KDM4EGPR119
SCHEMBL27359025 0.81 GPR119 (0.55) TP53POLBALDH1A1MEN1LMNA
SCHEMBL12058893 0.81 MAPT (0.45) TP53POLBLMNAGAAGPR119
SCHEMBL19078379 0.80 MGLL (0.43) TP53POLBALDH1A1MEN1LMNA
SCHEMBL17305170 0.80 GPR119 (0.43) TP53POLBHPGDGPR119TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4561575-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME Cedilla Therapeutics, Inc. (US) 2025-06-04 EP disclosed