Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 11/20 | 0.48 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30737029 | 0.89 | CACNA1H (0.54) | CACNA1HDRD2JAK2JAK1SIGMAR1 | |
| SCHEMBL23775686 | 0.84 | CACNA1H (0.52) | CACNA1HDRD2JAK2JAK1SIGMAR1 | |
| SCHEMBL32683928 | 0.82 | CACNA1H (0.55) | CACNA1HDRD2JAK2JAK1SIGMAR1 | |
| SCHEMBL5031510 | 0.81 | DRD2 (0.47) | CACNA1HDRD2JAK2JAK1SIGMAR1 | |
| SCHEMBL25329388 | 0.81 | ALDH1A1 (0.44) | EPHX1 | |
| SCHEMBL30736943 | 0.80 | CACNA1H (0.51) | CACNA1HDRD2JAK2JAK1SIGMAR1 | |
| SCHEMBL14708214 | 0.80 | CACNA1H (0.52) | CACNA1HDRD2JAK2JAK1SIGMAR1 | |
| SCHEMBL31301242 | 0.79 | DRD2 (0.63) | CACNA1HDRD2SIGMAR1EPHX1 | |
| SCHEMBL31657251 | 0.79 | KDM4E (0.46) | EPHX1 | |
| SCHEMBL30737178 | 0.79 | DRD2 (0.60) | CACNA1HDRD2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4580405-A1 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | Oerth Bio LLC (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024050016-A9 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | OERTH BIO LLC (US) | 2025-04-03 | — | — | WO | disclosed |
| WO-2025049555-A1 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | OERTH BIO LLC (US) | 2025-03-06 | — | — | WO | disclosed |
| WO-2024050016-A1 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | OERTH BIO LLC (US) | 2024-03-07 | — | — | WO | disclosed |