SCHEMBL30737121

SCHEMBL30737121

COC(=O)CCCCN1CCN(CCNC(=O)OC(C)(C)C)CC1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 11/20 0.54
CACNA1H O95180 1/20 0.53
SIGMAR1 Q99720 3/20 0.50
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
PAOX Q6QHF9 1/20 0.41
FPR3 P25089 1/20 0.41
FPR2 P25090 1/20 0.41
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRM3 P20309 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5856688 0.90 DRD2 (0.59) DRD2CACNA1HSIGMAR1TDP1MEN1
SCHEMBL30737000 0.88 CACNA1H (0.54) DRD2CACNA1HSIGMAR1TDP1MEN1
SCHEMBL31301242 0.85 DRD2 (0.63) DRD2CACNA1HSIGMAR1TDP1MEN1
SCHEMBL5031510 0.85 DRD2 (0.47) DRD2CACNA1HSIGMAR1TDP1
SCHEMBL5856648 0.85 SIGMAR1 (0.66) DRD2CACNA1HSIGMAR1TDP1
SCHEMBL13202614 0.84 DRD2 (0.59) DRD2CACNA1HSIGMAR1TDP1MEN1
SCHEMBL829106 0.83 DRD2 (0.54) DRD2CACNA1HSIGMAR1TDP1MEN1
SCHEMBL30380480 0.83 TDP1 (0.59) DRD2CACNA1HSIGMAR1TDP1MEN1
SCHEMBL3524057 0.83 DRD2 (0.66) DRD2CACNA1HSIGMAR1TDP1MEN1
SCHEMBL30737178 0.83 DRD2 (0.60) DRD2CACNA1HSIGMAR1TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4580405-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL Oerth Bio LLC (US) 2025-07-09 EP disclosed
WO-2024050016-A9 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2025-04-03 WO disclosed
WO-2025049555-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2025-03-06 WO disclosed
WO-2024050016-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2024-03-07 WO disclosed