SCHEMBL30737162

SCHEMBL30737162

COC(=O)c1ccc(Oc2cccc3c(C(=O)NCCCN)cccc23)nc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.41
F10 P00742 1/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
ST14 Q9Y5Y6 1/20 0.41
HCRTR1 O43613 1/20 0.39
HPGD P15428 1/20 0.39
MAPK1 P28482 1/20 0.38
MAPK8 P45983 1/20 0.37
POLB P06746 1/20 0.37
AURKA O14965 1/20 0.37
LCK P06239 1/20 0.37
KDR P35968 1/20 0.37
TEK Q02763 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC1 Q13547 1/20 0.37
MCHR1 Q99705 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30737241 0.87 HDAC3 (0.37) HPGDPOLBAURKALCKKDR
SCHEMBL30737309 0.86 GABRA5 (0.41) HCRTR1HPGDMAPK1BRD4CCR1
SCHEMBL30737273 0.83 PLK1 (0.47) MAPK1AURKALCKKDRTEK
SCHEMBL30737086 0.78 PLK1 (0.38) POLBKMT2A
SCHEMBL30737283 0.73 PLK1 (0.45) AURKALCKKDRTEK
SCHEMBL30737390 0.73 PLK1 (0.44) MAPK8AURKALCKKDRTEK
SCHEMBL27302800 0.70 GRN (0.46) HPGDMAPK1MCHR1KMT2A
SCHEMBL19808827 0.69 HRH3 (0.48) MAPK1POLBKMT2A
SCHEMBL30737479 0.69 HPGDS (0.53) HPGDMAPK1AURKALCKKDR
SCHEMBL23474091 0.68 MAPK1 (0.45) HPGDMAPK1POLBLCKMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 EP disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 WO disclosed