SCHEMBL30737189

SCHEMBL30737189

COC(=O)c1ccc(Oc2cccc(OC3CCN(C(=O)OC(C)(C)C)CC3)c2)nc1

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 14/20 0.49
PRKAA2 P54646 1/20 0.47
PDE4A P27815 2/20 0.44
PDE4B Q07343 2/20 0.44
PDE4C Q08493 2/20 0.44
PDE4D Q08499 2/20 0.44
CHEK2 O96017 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7401143 0.86 GPR119 (0.62) GPR119PDE4APDE4BPDE4CPDE4D
SCHEMBL29826469 0.83 MEN1 (0.55) GPR119PDE4APDE4BPDE4CPDE4D
SCHEMBL2807130 0.83 MEN1 (0.55) GPR119PDE4APDE4BPDE4CPDE4D
SCHEMBL27233564 0.83 GPR119 (0.55) GPR119
SCHEMBL30737405 0.81 PRKAA2 (0.42) PRKAA2
SCHEMBL4913618 0.79 HRH3 (0.52)
SCHEMBL29053063 0.79 GPR119 (0.46) GPR119
SCHEMBL240683 0.79 GPR119 (0.61) GPR119PDE4APDE4BPDE4CPDE4D
SCHEMBL30737352 0.78 LMNA (0.44) PRKAA2
SCHEMBL5542864 0.78 USP30 (0.53) GPR119PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025133234-A1 SORTILIN BINDERS AND BIFUNCTIONAL COMPOUNDS THEREOF DRAUPNIR BIO APS (DK) 2025-06-26 WO disclosed
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 EP disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 WO disclosed