SCHEMBL30737405

SCHEMBL30737405

COC(=O)c1ccc(Oc2cccc(OC3CCNCC3)c2)nc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKAA2 P54646 1/20 0.42
LMNA P02545 1/20 0.42
WNT1 P04628 2/20 0.42
GSK3B P49841 2/20 0.42
DYRK1A Q13627 2/20 0.42
HRH1 P35367 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
BRCA1 P38398 1/20 0.42
HBB P68871 1/20 0.42
KMT2A Q03164 1/20 0.42
HSD17B10 Q99714 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
HRH3 Q9Y5N1 6/20 0.40
FAAH O00519 1/20 0.40
ALOX5AP P20292 1/20 0.40
FEN1 P39748 1/20 0.40
KCNH2 Q12809 1/20 0.39
EPHX2 P34913 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30737352 0.89 LMNA (0.44) PRKAA2LMNAKDM4EMEN1ALDH1A1
SCHEMBL30737189 0.81 GPR119 (0.49) PRKAA2
SCHEMBL2807802 0.80 EPHX2 (0.55) WNT1GSK3BDYRK1AHRH1L3MBTL1
SCHEMBL30737006 0.80 SORT1 (0.59) PRKAA2LMNAWNT1GSK3BDYRK1A
Hydrochloric Acid SCHEMBL14127514 0.79 EPHX2 (0.54) WNT1GSK3BDYRK1AHRH1ALDH1A1
SCHEMBL27234555 0.77 FAAH (0.54) FAAH
SCHEMBL30737193 0.77 LMNA (0.51) LMNAKDM4EMEN1ALDH1A1BRCA1
SCHEMBL31646829 0.76 L3MBTL1 (0.54) LMNAKDM4EMEN1ALDH1A1KMT2A
SCHEMBL693093 0.76 HRH3 (0.59) LMNAKDM4EMEN1ALDH1A1BRCA1
SCHEMBL31646216 0.75 MAPT (0.50) LMNAKDM4EMEN1ALDH1A1BRCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025133234-A1 SORTILIN BINDERS AND BIFUNCTIONAL COMPOUNDS THEREOF DRAUPNIR BIO APS (DK) 2025-06-26 WO disclosed
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 EP disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 WO disclosed