SCHEMBL30737267

SCHEMBL30737267

CC(=O)NCCn1cc(-c2cccc(O)c2)nn1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 15/20 0.48
HDAC4 P56524 15/20 0.48
HDAC1 Q13547 15/20 0.48
HDAC7 Q8WUI4 15/20 0.48
HDAC2 Q92769 15/20 0.48
HDAC10 Q969S8 15/20 0.48
HDAC11 Q96DB2 15/20 0.48
HDAC8 Q9BY41 15/20 0.48
HDAC6 Q9UBN7 15/20 0.48
HDAC9 Q9UKV0 15/20 0.48
HDAC5 Q9UQL6 15/20 0.48
ALOX5 P09917 1/20 0.47
HSD17B1 P14061 1/20 0.46
HSD17B2 P37059 1/20 0.46
IDO1 P14902 1/20 0.45
CD74 P04233 1/20 0.44
MIF P14174 1/20 0.44
ABL1 P00519 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30737158 0.84 HDAC3 (0.45) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL30737470 0.78 ALOX5 (0.57) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL18760619 0.77 ALOX5 (0.56) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL30737254 0.77 ALOX5 (0.51) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL12986809 0.77 ALOX5 (0.56) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL19690458 0.76 HDAC8 (0.54) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL16238536 0.76 UCHL5 (0.52) HDAC3HDAC4HDAC1HDAC7HDAC2
Water SCHEMBL16279409 0.76 ALOX5 (0.55) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL30737278 0.75 HDAC3 (0.45) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL30737131 0.74 HDAC3 (0.47) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 EP disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 WO disclosed