SCHEMBL30737306

SCHEMBL30737306

O=C(ON1C(=O)CCC1=O)c1ccc2c(Br)cccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 1/20 0.48
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
PTPN1 P18031 1/20 0.36
MAPK1 P28482 1/20 0.35
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
LCK P06239 1/20 0.33
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MGLL Q99685 1/20 0.32
CBX7 O95931 1/20 0.32
CDYL2 Q8N8U2 1/20 0.32
CDYL Q9Y232 1/20 0.32
CDY1; CDY1B Q9Y6F8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1231850 0.80 CES2 (0.49) KMT2AMEN1PTPN1MAPK1ALDH1A1
SCHEMBL12444640 0.79 CES2 (0.43) KMT2AMEN1MAPK1HPGDLMNA
SCHEMBL14860981 0.78 MAPK1 (0.48) KMT2ARXFP1MAPK1ALDH1A1MAPT
SCHEMBL1284775 0.77 ALDH1A1 (0.49) KMT2APTPN1MAPK1ALDH1A1MAPT
SCHEMBL12444650 0.76 KMT2A (0.49) KMT2AMEN1MAPK1ALDH1A1MAPT
SCHEMBL4897945 0.76 CA12 (0.46) KMT2AMAPK1ALDH1A1MGLL
SCHEMBL5762353 0.76 LCK (0.56) SLC9A1LCK
SCHEMBL30737187 0.75 PRNP (0.44) KMT2AMEN1ALDH1A1MAPTMGLL
SCHEMBL300884 0.74 CA12 (0.42) KMT2AMEN1MAPK1ALDH1A1MAPT
SCHEMBL11591873 0.74 MAPT (0.39) KMT2AALDH1A1MAPTHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 EP disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 WO disclosed