SCHEMBL30737358

SCHEMBL30737358

C#CCC(O)c1cccc(O[Si](C)(C)C(C)(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
CA12 O43570 4/20 0.35
CA1 P00915 4/20 0.35
CA9 Q16790 4/20 0.35
CHRM2 P08172 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3280559 0.83 LMNA (0.43) AOC3L3MBTL1CA12CA1CA9
SCHEMBL6781597 0.83 PNMT (0.48) AOC3L3MBTL1CA12CA1CA9
SCHEMBL15195453 0.79 AOC3 (0.59) AOC3L3MBTL1CHRM2CHRM1CHRM3
SCHEMBL343105 0.79 CA12 (0.40) AOC3L3MBTL1CA12CA1CA9
SCHEMBL15242469 0.75 CA1 (0.42) CA12CA1CA9HSP90AA1HSP90AB1
SCHEMBL9643548 0.75 ALOX5 (0.39) AOC3L3MBTL1CA12CA1CA9
SCHEMBL19745616 0.74 CA12 (0.41) L3MBTL1CA12CA1CA9HSP90AA1
SCHEMBL8076860 0.74 CA12 (0.37) CA12CA1CA9HSP90AA1HSP90AB1
SCHEMBL4576566 0.73 CA12 (0.36) CA12CA1CA9HSP90AA1HSP90AB1
SCHEMBL18540700 0.73 BRD4 (0.37) AOC3CA12CA1CA9HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 EP disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 WO disclosed