Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 4/20 | 0.55 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.49 |
| ▸ | ERN1 | O75460 | 2/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186327 | 0.83 | PTPN1 (0.68) | PLAUHSD17B1HSD17B2ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL3917256 | 0.81 | PTPN1 (0.66) | PLAUHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL10970308 | 0.81 | ALDH1A1 (0.66) | PLAUHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL3917253 | 0.81 | PLAU (0.52) | PLAUHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL29463701 | 0.81 | ALDH1A1 (0.62) | PLAULCKPARP1PTPN1SLC9A1 | |
| SCHEMBL13045132 | 0.81 | PARP1 (0.50) | PLAULCKPARP1ERN1GRIN2D | |
| SCHEMBL6384957 | 0.81 | ALDH1A1 (0.62) | PLAULCKPARP1PTPN1SLC9A1 | |
| SCHEMBL29090844 | 0.81 | ALDH1A1 (0.59) | PLAUHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL3171151 | 0.80 | SLC9A1 (0.69) | PLAULCKPARP1ERN1PTPN1 | |
| SCHEMBL13333371 | 0.80 | PARP1 (0.52) | PLAULCKPARP1PTPN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543858-A1 | BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES | Draupnir Bio ApS (DK) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023247754-A1 | BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES | DRAUPNIR BIO APS (DK) | 2023-12-28 | — | — | WO | disclosed |