Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 2/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30737068 | 1.00 | GRN (0.45) | GRNSORT1MAPTAKR1C3F2 | |
| SCHEMBL30737356 | 0.89 | L3MBTL1 (0.53) | GRNSORT1MAPTPPARGGAA | |
| SCHEMBL31646784 | 0.82 | GRN (0.45) | GRNSORT1MAPTLOXL2PPARG | |
| SCHEMBL31646829 | 0.81 | L3MBTL1 (0.54) | MAPTAKR1C3F2F10LOXL2 | |
| SCHEMBL30737460 | 0.80 | F10 (0.56) | GRNSORT1MAPTAKR1C3F2 | |
| SCHEMBL30803809 | 0.79 | MAPT (0.51) | GRNSORT1MAPTAKR1C3F2 | |
| SCHEMBL4254797 | 0.79 | KDM4E (0.61) | MAPTGAAALDH1A1MEN1CASP3 | |
| SCHEMBL31646600 | 0.78 | LOXL2 (0.46) | GRNSORT1MAPTLOXL2GAA | |
| SCHEMBL31646343 | 0.77 | GRN (0.52) | GRNSORT1MAPTGAAALDH1A1 | |
| SCHEMBL1271501 | 0.77 | MAPT (0.57) | GRNSORT1MAPTAKR1C3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025133234-A1 | SORTILIN BINDERS AND BIFUNCTIONAL COMPOUNDS THEREOF | DRAUPNIR BIO APS (DK) | 2025-06-26 | — | — | WO | disclosed |
| EP-4543858-A1 | BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES | Draupnir Bio ApS (DK) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023247754-A1 | BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES | DRAUPNIR BIO APS (DK) | 2023-12-28 | — | — | WO | disclosed |