SCHEMBL30737477

SCHEMBL30737477

CC(=O)NCCOc1cccc(Oc2ccc(C(=O)ON3C(=O)CCC3=O)cn2)c1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 5/20 0.48
MTNR1B P49286 4/20 0.48
USP2 O75604 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
HSD17B10 Q99714 1/20 0.40
ACACB O00763 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
POLB P06746 1/20 0.39
HRH3 Q9Y5N1 1/20 0.38
LIPG Q9Y5X9 1/20 0.37
ACACA Q13085 2/20 0.37
OXTR P30559 1/20 0.37
AVPR1A P37288 1/20 0.37
AVPR1B P47901 1/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30737320 0.86 ROCK2 (0.40) ACACBHRH3
SCHEMBL30737532 0.81 HDAC3 (0.40) MTNR1AACACB
SCHEMBL3688798 0.78 HRH3 (0.50) HRH3
SCHEMBL30737491 0.75 MTNR1A (0.49) MTNR1AMTNR1BUSP2ALOX15TSHR
SCHEMBL30737432 0.73 CA12 (0.44) MTNR1AMTNR1BL3MBTL1POLBKDM4E
SCHEMBL31646216 0.72 MAPT (0.50) MAPK1HSD17B10L3MBTL1KDM4E
SCHEMBL31724715 0.70 ROCK1 (0.47) ACACBL3MBTL1
SCHEMBL31724770 0.69 BCHE (0.44) TSHRKDM4E
Acetone SCHEMBL1019109 0.68 MAPK1 (0.40) MAPK1L3MBTL1KDM4E
SCHEMBL30737383 0.68 MAPT (0.45) TSHRMAPK1HSD17B10L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 EP disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 WO disclosed